ANALYSIS OF MORBIDITY OF COLORECTAL CANCER IN REPUBLIC OF TAJIKISTAN

ANALYSIS OF MORBIDITY OF COLORECTAL CANCER IN REPUBLIC OF TAJIKISTAN

*Rasulov S.R., **Karimov A.M.

ANALYSIS OF MORBIDITY OF COLORECTAL CANCER IN REPUBLIC OF TAJIKISTAN

*Department of Oncology of the State Educational Establishment «Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan»

**State Establishment "Republican Oncological Scientific Center” of the Ministry of Health and Social Protection of population of Republic of Tajikistan

Aim. To perform statistical analysis and identify the most characteristic features of colorectal cancer in the population of Republic of Tajikistan.

Materials and methods. Clinical data of 115 patients with colorectal cancer in the age of 18 to 92 years, who were treated in department of oncoproctourology of State Establishment "Republican Oncological Scientific Center" of Ministry of Health of Republic of Tajikistan in 2012 was studied. Tumor morphologically verified in all patients. In a planned regularity were hospitalized 89 patients, by emergency indications — 26 patients. To all performed endoscopy of the intestine, ultrasonic and review roentgenologic researches of the abdomen.

Results. Frequency of morbidity is somewhat more among males (52,2%). Peak of morbidity occurs in the age of 50-69 years (46,9%). Up to 40 years colorectal cancer diagnosed in 14,8%, over the age of 70 years — in 18,3%. In the majority of cases the tumor located in rectum (67%), then in sigmoid — 9,6%, in downstream parts of the large bowel — 6,1% and less in transverse section — 0.9%. Patients with early stages of tumor development (T1-2N0-1M0) constituted only 9,1%. In 67,3% of patients established locally advanced process, 23,6% had distant metastases. Metastases often observed in liver (42,3%) in liver and lung (23,1%), in peritoneum (19,2%) and less in skeletal bones and distant lymph nodes. Intestinal obstruction was observed in 17,4% of patients, intestinal bleeding — in 5,2%.

Conclusion. The most frequent localization of colorectal cancer is in straight line, then in sigmoid colon and in cae¬cum. Peak of morbidity occurs in the age of 50-69 years (46,9%). In the primary appeal for medical assistance 89,1% of patients had locally advanced (67,3%) or generalized (21,8%) process.

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