POSITIVE INFLUENCE OF SORBITOL IN PATIENTS WITH CHRONIC RENAL FAILURE

POSITIVE INFLUENCE OF SORBITOL IN PATIENTS WITH CHRONIC RENAL FAILURE

Bobieva N.H., Gadoev S.H., Subhonova Z.I., *Sunatulloev D.S.

POSITIVE INFLUENCE OF SORBITOL IN PATIENTS WITH CHRONIC RENAL FAILURE

Department of Internal Disease № 3 of the Tajik Medical State University named after Abuali-ibn-Sino

*Department of Therapy of the State Education Establishment “Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan”

Aim.To estimate actions of sorbitol in combination with enterosorbents on gastrointestinal tract in the complex treatment of chronic renal failure.

Materials and methods. The study included 40 patients with chronic renal failure. Diagnosis and assessment of severity of uremia was conducted by determination of glomerular filtration rate (the level of urea and creatinine in blood), the A / D profile and the degree of edemas.

Results. In patients on background of reception of sorbitol 10-15 days earlier than in the control group, marked decrease in the level of nitrogenous wastes in the peripheral blood (urea, creatinine), reduction of edemas, reduction of hypertension. Reception of sorbitol accompanied by a decrease symptoms of uremic intoxication and improvement of the patient. Improvement comes after 7-10 days of treatment. This is manifested in decrease of pruritus, nausea and vomiting, headache and decrease in levels of nitrogenous wastes in the peripheral blood. Wellness at reception of sorbitol saved from 1 to 6 or even 12 months.

Conclusion. The use of sorbitol in combination with other enterosorbents significantly complements traditional dialysis therapy, hemodialysis pushing the starting date.

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