EFFECTIV TREATMENT OF URINARY TRACT INFECTIONS IN PRIMARY CARE IN THE PRACTICE OF FAMILY PHYSICIAN

EFFECTIV TREATMENT OF URINARY TRACT INFECTIONS IN PRIMARY CARE IN THE PRACTICE OF FAMILY PHYSICIAN

Nazirova N.K., Mirzoeva Z.A., Vositzoda Z.F.

EFFECTIV TREATMENT OF URINARY TRACT INFECTIONS IN PRIMARY CARE IN THE PRACTICE OF FAMILY PHYSICIAN

Department of Family Medicine of the State Educational Establishment «Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan»

Aim. Evaluate the effectiveness of schemes treatment of urinary tract infections UTI based on the principles of evidence-based medicine.

Materials and methods. We observed 28 patients with UTI, with average age 23,3±2,4 years. Children and adolescents comprised 42,9% (12 people), adults — 57,1% (16 people), among them women — 60,7%, men — 39,3%. Methods applied: clinical and statistical.

Results. Among those who were diagnosed UTI first established in 11 people (39,3%): acute cystitis observed among 63,6% (7 people), acute pyelonephritis — 36,4% (4 people). Patients with recurrent episodes of UTI comprised 60,7% (17 people): 58,8% (10 people) with cystitis, 41,2% (7 people) with pyelonephritis. 71,4% of cases of recurrent episodes of pyelonephritis were observed in patients with urolithiasis.UTI was treated with consideration of gender, age and diagnosis. Children younger than 12 years with cystitis and pyelonephritis received amoxicillin in combination with clavulanic acid 20-40 mg/kg per day in 3 divided doses for 5 (7-10) days. All patients older than 12 years received 100 mg of nitrofurantoin 2 times a day for 5 days (level of evidence A) or 500 mg of ciprofloxacin (alternative) 2 times a day 3-5 (7-10) days. Patients with recurrent UTI after adequate therapy and bacterial eradication were received long-term prophylaxis with nitrofurantoin, as 50 or 100 mg at bedtime for 6-12 months. As a result of treatment, based on evidence-based medicine, we observed positive dynamics of clinical and laboratory manifestations of UTI.

Conclusion. There is a necessity of strict adherence to the recommended schemes in accordance with the conclusive data, and avoidance of excessive use of antimicrobial drugs and use antibiotics without evidence.

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