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СЛОВО ГЛАВНОГО РЕДАКТОРА
Наше издание является научно-практическим журналом, в котором публикуются основные научные результаты диссертаций на соискание ученой степени кандидата и/или доктора медицинских наук как нашего института, так и других лечебно-учебных медицинских учреждений, интересные случаи из практики, обзоры литературы, лекции и юбилейные статьи. Журнал выходит 4 раза в год, и каждый номер имеет не менее 80 страниц. Каждая поступающая статья принимается по требованиям, проходит строгий отбор и отдается для выпуска в номер только после рецензирования и обязательного редактирования.
У нас принято одностороннее слепое рецензирование. Рецензенты уделяют особое внимание содержанию статьи и проверке данных статистической обработки, их соответствие современным требованиям.Главный редактор журнала доктор медицинских наук Мухиддинов Н. Д.
TREATMENT AND PREVENTION OF VIRAL INFECTIONS WITH THE USE OF INTERFERON INDUCTORS
MIRZOYEVA Z.A., KHISOMOVA KH.K.
THE DEPARTMENT OF FAMILY MEDICINE TIPGPMP
Today viral infections are the leading cause of morbidity worldwide, the role of which in the overall morbidity will only increase. Recently in the treatment of viral infections extensive use of immunomodulators, the range is constantly expanding. The most promising drugs in the given as¬pect are interferon inducers. The article presents the results of studies of prophylactic effectiveness and treatment of acute respiratory viral infections interferon inducers of 150 patients aged from 1 month to 17 years. The results obtained showed that anaferon having a pronounced curative and prophylactic efficiency of the flu, when before vaccine period increases the functional activity of specific antibodies that reduce the intensity of morbidity. The ability of the drug to reduce the number of bacterial complications allowed authors to effectively apply anaferon in the treatment of viral infections in children with secondary immunodeficiency condition. The inclusion of anaferon in the standard therapy of acute intestinal virus infection in children significantly reduced the duration of the main symptoms of the disease.
SOME FACTORS AFFECTING IN THE MALYARIOLOGY SITUATION IN PREDELIMNATION PERIOD IN THE REPUBLIC OF TAJIKISTAN
SHARIPOV A.A., NARZULOEVA M.F.
THE DEPARTMENT OF INFECTIOUS DISEASES, EPIDEMIOLOGY, HYGIENE AND ENVIRONMENTAL PROTECTION TIPGPMP
antimalarial drugs. Since the beginning of the 90s in the Republic of Tajikistan epidemiological malaria situation started to deteriorate due to the mass migration of refugees on the territory of Afghan¬istan and their subsequent return to their former place of residence, the sharp weakening of the work of the General and special services, and the conductors real absence of measures to fight against carriers of infection due to economic instability in the Republic of Tajikistan. The article was to study the epidemio¬logical features of the spread of malaria in the Republic of Tajikistan and the factors affecting the malarial situation in preelimination period. The situational analysis is based on data archival materials, annual reports district, regional and Republican centers for combating tropical diseases. Analysis of the archival documents showed that in 1994 and 1995 officially registered 2411 and 6103 cases pathology, respectively, reaching values 29794 patients in 1997. In 2005 as a result of anti-malaria activities registered 2309 malaria cases, in 2008 – 318, in 2010 – 112, in 2011 – 78 and in 2012 – 33 cases. In 2013, however, the incidence of malaria has increased in 1,6 times in comparison with 2012, that is connected with rapid development of road transport infrastructure, construction of new bridges connecting the two States.
The epidemic situation of malaria in the last decade was complicated by the advent of pathogen resis¬tance to
COMPARATIVE ASSESSMENT OF RESULTS OF A TRADITIONAL AND LAPAROSCOPIC CHOLECYSTECTOMY
Aim. Сomparative assessment of effectiveness of a traditional and laparoscopic cholecystectomy at a cloelithiasis.
STUDY OF THE IMPLEMENTATION OF NATIONAL STANDARDS FOR ANTENATAL CARE FOR PREGNANT WOMEN
SAMADOVA G.A., MULLOEV A.M., DODOBAEVA B.S.
THE DEPARTMENT OF NURSE WORK IN FAMILY MEDICINE TIPGPMP
DEPARTMENT OF PUBLIC HEALTH, ECONOMY AND MANAGEMENT BY PUBLIC HEALTH WITH COURSE OF THE MEDICAL STATISTICS TIPGPMP
Over the past two years the birth rate in the Republic of Tajikistan ranged 29,3-by 28,7 per 1,000 popu¬lation. Along with high fertility, maternal mortality was 45,0 is 37,0 per 100,000 liveborns, the main reasons for which 25% of the cases considered bleeding, 15% and 12% – gynecological infections and eclampsia. The picture presented defined the purpose of the present research is to study the indicators of National standards of antenatal care for pregnant women with an analysis of the correlation between them. Under the supervision were 72 pregnant women aged from 17 to 40 years of age, living in one of the areas with a population of 1722 person. Analysis of work of specialists in antenatal care among women up to 12 weeks of pregnancy showed that only 47,2% of the total number of timely addressed to specialists and were taken to the dispensary registration. In the later stages of pregnancy 52,8% of women with repeated pregnancies are under dispensary observation. The majority of women in a timely manner became the dispensary reg¬istration pregnancy, were the original inhabitants of the area under study. The reason of late treatment of women with a long pregnancy, with a view to their taking on dispensary account that is linked with the arrival of hard-to-reach areas of the Republic. The obtained results allow to predict the state of pregnancy and timely to organize a correction of care for prevention of possible antenatal complications.
REGIONAL FACTORS OF DISTRIBUTION OF INFECTIONS, SEXUALLY TRANSMITTED
Aim. To study data on the regional factors promoting increase in prevalence of urogenital chlamidiosis.
PERFORMANCE EVALUATION DIAGNOSTIC CENTERS AT THE PRESENT STAGE
SAFAROV Z.SH., AHMEDOV A. A., SAFAROVA T.M.
NDC MPH RT
DEPARTMENT OF PUBLIC HEALTH, ECONOMY AND MANAGEMENT BY PUBLIC HEALTH WITH COURSE OF THE MEDICAL STATISTICS TIPGPMP
At the present stage of development the aim of the health system is the organization of qualita¬tive models of infrastructure and management schemes. In the given aspect the most urgent health problem is to build a high-quality system of medical care. The article summarizes the results of the situational analysis of medical activities and evaluation of diagnostic services at the present stage in the conditions of state financing and transition to full cost accounting in the Republic of Tajikistan. Analysis of normative-legal documents showed that of 2866 institutions of primary health care 3,8% of them are represented by the district and city health centers, 26,5% of rural health centers, 10,8% in the specialized outpatient centers, 58,9 per cent – houses of health. Analysis of the equipment of the medical equipment in the period 1990-2011, showed that mostly diagnostic equipment prevailed in medical-preventive institutions, Dushanbe and Sughd regions (25,4% and 23,8%). On the balance of research institutions, Republican specialized hospitals and centres, it amounted to 19,9%. Oth¬er administrative territories of the Republic of equipment diagnostic equipment was significantly lower. Analysis of the activity of the services on provision of diagnostic help to the population of the Republic of Tajikistan in the modern socio-economic conditions showed that the main factors in the development of diagnostic centers and efficiency of delivered medical assistance are: good governance, improving financing with the purpose of modernization, improvement of quality and successful use of personnel and technological potential.
TO QUESTION ABOUT CONDITION OF THE MARGINALADAPTATION OF FILLING MATERIALS WHEN UNDERTAKING RECONSTRUCTION TREATMENT OF TOOTH CARIES
Aim. A comparative estimation of the influence of the different measures of the preventive maintenance on perme¬
ability of the border in system “teeth-filling”.
DYNAMICS IMMUNOLOGICAL INDICES IN PATIENTS OF CHRONIC GENERALIZED PERIODONTITIS DURING THERAPY WITH MELLINOL
AKHROROVA Z.K., KOMILOV F.M., NOSIROV A.F., FAYZOV K.S.
THE DEPARTMENT OF ORTHOPEDIC STOMATOLOGY TIPGPMP
With the purpose of correction of immunological changes in dental patients has been studied the influence of the drug mellinol in the treatment of generalized periodontitis in 32 patients with chronic viral hepatitis b and C. The results obtained show that in the group of patients with chronic viral hepatitis b and C using the drug significantly increased rates of T-lymphocyte subpopula¬tions of T-helpers, a marked increase the number of B-lymphocytes and natural killer cells, and increased the number of cells expressing a chain of the IL-2 receptor and receptor to transferrin that shows a marked improvement periodontal status among the surveyed population. Initially reduced rates of T-lymphocytes and T-helpers, expression markers of activation, as a manifestation of immune dysfunction in patients with chronic viral hepatitis b and C, during the therapy with mellinol significantly increased. When using the drug in the least degree of expression is subjected to a subpopulation of cytotoxic T-lymphocytes, which are responsible for the clearance of the virus and the production of cytokines, controlling viral replication. It is revealed that the immunotropic effects of the drug mellinol of periodontal patients with chronic viral hepatitis b and C is manifested positively, regardless of the type of virus that caused the disease, and correlates with the notable restoration of fabrics of parodont.
Endodontic aspects of the treatment of endoparodontal syndrome (review of the literature)
Turaev N.G., Ismoilov A.A., Ashurov G.G.
In presented work organized analytical estimation nearest and remote results of endodontic’s treatments of the teeth. Stated material are indicative of that that improvement modern and development new endodontic methods of the treatment teeth will allow to conduct the well-timed diagnostics an endoparodontal syndrome and select the efficient methods its early preventive maintenance.
ULTRASOUND DIAGNOSTICS THYROID PATHOLOGY IN CHILDREN AND ADOLESCENTS
KASYMOVA S.D., AYUBOVA G.SH., RAHMONOV V.D., BOYMATOVA M.B.
THE COURSE OF ENDOCRINOLOGY AT DEPARTMENT OF THERAPY TIPGPMP REPUBLICAN CLINICAL CENTRE OF ENDOCRINOLOGY
In connection with the exceptional importance of the thyroid gland problem of pathology of the organ of children is the focus of endocrinologists. Pathology of the thyroid gland in the regions of iodine deficiency, which includes the Republic of Tajikistan, occupies the leading position in the endocrine pathology in children and adolescents. Diagnostics of thyroid pathology in this category includes a phased investigation with the decision of the question concerning the goitrous increase the authority and assessment of the functional state of the thyroid gland. Many tasks successfully done with the use of ultrasonic technologies. The article suggests the use of ultrasound diagnostics for estimation of structural and functional changes of the thyroid gland, 93 children and adolescents with a duration of pathology from 6 months to 2 years. Depending on the functional state of the examined organ children and adolescents were divided into the following groups: I group amount¬ed to 61,3% of patients with diffuse nontoxic goiter, II – 20,4% of individuals autoimmune, with tireoidita III group – 18,2% of surveyed with hypopituitarism thyroid gland. Results of ultrasonic research show the greatest increase in volume of the thyroid gland in the group 2 patients with au¬toimmune thyroiditis. Analysis of results of ultrasonic research showed that in the 1 group of the examined enlargement of the thyroid gland was moderately expressed. The largest increase of the volume of the thyroid was noted in group 2 patients with autoimmune thyroiditis. Of the 17 patients with subclinical hypothyroidism last group in 58% of cases of thyroid volume slightly increased in 42% of cases, the value remains in the normal range. The results obtained allow to note that for the estimation of structural and functional changes of the thyroid gland are essential ultrasound diagnostics.