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СЛОВО ГЛАВНОГО РЕДАКТОРА
Наше издание является научно-практическим журналом, в котором публикуются основные научные результаты диссертаций на соискание ученой степени кандидата и/или доктора медицинских наук как нашего института, так и других лечебно-учебных медицинских учреждений, интересные случаи из практики, обзоры литературы, лекции и юбилейные статьи. Журнал выходит 4 раза в год, и каждый номер имеет не менее 80 страниц. Каждая поступающая статья принимается по требованиям, проходит строгий отбор и отдается для выпуска в номер только после рецензирования и обязательного редактирования.
У нас принято одностороннее слепое рецензирование. Рецензенты уделяют особое внимание содержанию статьи и проверке данных статистической обработки, их соответствие современным требованиям.Главный редактор журнала доктор медицинских наук Мухиддинов Н. Д.
EVENT OF COMPLICATED HYPOTHIREOS
ASTANOVA M.K., NUMANOVA M.A.
In article considered the event of hypothireos average gravity, complicated with hepatomegaly, chronic cholecistopancreatit, pericarditis. Varied manifestations of the syndrome of hypothireos quite often serves central to wrong diagnosis, somet
THE MORPHOLOGY OF MICROVASCULARCHANNEL A LARGE GLAND DOG IN NORM AND IN CASE OF PERITONITIS IN THE CONDITIONS OF THE PLATEAU
MIRZOEV KH.M., ZOKIROV R.KH., PULADOV A.KH., KARIMOV S.S.
Study of the regularities of the structure of the structural organization of microvascular channel a large gland dog in norm and in case of peritonitis in the conditions of the plateau, showed that the presence of high-grade microvascularnetwork in a large gland, ensures a high level of metabolism and is evidence of the involvement of his in the processes of filtra¬tion, resorption of serous fluid abdominal cavity and protective functions. Morphological, hemodynamic and morphometric changes microvascular channel omentum and their in¬crease in peritonitis due to the toxicity of the blood of experimental animals, because the later stages of peritonitis in the blood circulate products of destruction of bacteria-endotoxins and biologically active the substance of the damaged tissue.
USING THE METHOD OF THE TISSUE ENGINEERING ON BASE OF THE ALLOY NIKELID TITANIUM AT TREATMENT THE PATIENS WITH BENIGNANT NEW FORMATIONS OF THE BONES MAXILLOFACIAL AREA
Aim. To improve the tacticians of surgical treatment of the patients with benignant neoplasms (new formations) of the bones of maxillofacial area using the tissue engineering method on the basis of the small-pelleted nikelid titanium.
OPTIMIZATION OF THE PREVENTION OF COMPLICATIONS AND TREATMENT OF DAMAGE TO THE SKELETON AT THE POLYTRAUMA
SIRODJOVK.KH., AKHMEDOVSH.M., RAXIMOV A.T., TOLIBOVSH.M., ESHONOV I.B.
Through the use of optimized complex diagnostics of acute period polytrauma, by deter-mining the fat globulemia on roots in 43 patients, and treatment of purposeful application of the solution rheomacrodex with combination with curantylum, glucose-novocaine mixture intravenously along with specific therapy globulemia, managed to reduce the number of complications in comparison with indexes in the control group.
INFLUENCE OF MELDONY ON CARDIOTOXITY OF DOXORUBICINE IN PATIENTS WITH ACUTE LEUKEMIAS
RASULOV U.R., SHARIFOV M.M., SHAMSOV A.T., KHASANOV D.M., RAKHIMOV B.R., SUN’ATULLOEV D.S.
THE DEPARTMENT OF THE INTERNAL DISEASES №3 TSMU BY NAME ABUALI IBN SINA THE DEPARTMENT OF THERAPY WITH COURSE OF THE ENDOCRINOLOGY TIPGPMP
Acute leukemia, as a rare disease, is only 3% of human malignancies. The aim of treatment of acute leukemia is eradication of leukemic clone restore normal blood, achieveming long-term disease free survival of patients. This is achieved through the use of myelotoxical anticancer drugs that cause deep aplasia haemopoesis. In the present
paper summarises the results of the antitumor antibiotic antratcycline stimulants doxorubicin, with a joint appointment cardioprotector meldony. Under the supervision were 147 patients with acute leukemia. Among the observed patients 85 people received chemotherapy initially, 62 people – previously been subjected to chemotherapy effects. For the induction of remission patients of the 1st group was appointed polychemotherapy by the scheme “7+3”. Patients in group 2 received similar polychemotherapy together with cardioprotector Mildronate. During the treatment of patients of group 1 in 32% of cases were observed sinus tachycardia, atrial and ventricular arrhythmia, changes in segment ST, 7% of cases developed a complete atrioventricular block that shows the development of early cardiac toxicity of doxorubicin. In 19,04% of cases in patients of group 2 were observed ventricular tachycardia, and changes in segment ST.
Youth and their reproductive health
Nurmatova Z.I., Nurmatov А.А., Yusupova M.R.
As a result of research it is established that reproductive health is influenced by such factors, as a somatic and gynecologic pathology. It once again confirms necessity for timely informing of youth on problems of reproductive health and increase of their responsibility for own health. Themes on preservation of the health which excite youth, were various – questions of effective contraception, abortions and their consequences, preventive maintenance, a HIV of an infection, oncological diseases of genitals. Thus, results of socially-psychological diagnostics of personal factors of reproductive behavior allow to approach to deeper understanding of values of reproductive health of youth, desires, motives, expectations, инициаций in decision-making at modern young men and girls of reproductive age, and also to develop adequate practical psihologo-social recommendations and effective technicians of work with young men. It once again confirms necessity for timely informing of youth on problems of reproductive health and increase of their responsibility for own health.
The complex of multifunctional solution reosorbilakt in intensive therapy with endogenous intoxication in patients with acute peritonitis.
Khamidov D.B. , Kosimov Z.K. , Khаmidov D.D., Kiyamоv S.E.
In 67 patients with acute peritonitis studied the degree of endogenous intoxication. The efficiency of complex polyfunctional solution reosorbilakt included in the program of infusion therapy for correction of endogenous intoxication in patients with acute peritonitis
МИЛДРОНАТ® В КОМПЛЕКСНОЙ ТЕРАПИИ ИШЕМИЧЕСКОЙ БОЛЕЗНИ СЕРДЦА В УСЛОВИЯХ ВЫСОТНОЙ ГИПОКСИИ
* RAKHIMOV Z.YA., **KUDRATBEKOVA., * NARZULLAYEVA A.R.
**CARDIOLOGISTS ASSOCIATION OF THE REPUBLIC OF TAJIKISTAN
*DEPARTMENT OF CARDIOLOGY WITH THE COURSE OF CLINICAL PHARMACOLOGY TIPGPMP
The article is devoted to the study of the use of Meldrony in 30 patients with chronic coronary heart disease, stable angina of II-III class combined with arterial hypertension of II degree with high and very high risk of cardiovascular complications in conditions, Midlands Gorno-Badakhshan Autonomous region of Tajikistan. Among the examined patients on the background of the drug Meldrony in a daily dose of 1000 mg, showed a significant improvement cardiohaemodynamic indicators. Simultaneously, a decrease of the average frequency of angina attacks a day with 2,77±0,26 to 1,52±0,17. Also noted a decrease of the daily quantity of consumed nitroglycerin from 2,4 to±0,23 to 1,4±0,16 and significant increase of tolerance to physical activity detected test 6-minute walk from 388±33 m up to 512±39 m Significantly increased the degree of shortening the anterior-posterior size of the left ventricle and the speed of the circular of the shortening of the fibres infarction. Examine the safety and efficacy of the use of Meldrony patients with stenocardia voltage conditions, Midlands Pamir confirmed distinct antianginal its properties.
EVALUATING THE EFFECTIVENESS OF MEASURES COUNTERACTION DRUG DEPENDENCE IN REPUBLIC OF TAJIKISTAN
Aim. Evaluation of the effectiveness of existing measures designed at preventing drug use, in particular women.
Earnoseconjunctival syndrome, reality and means under fungal sinusitis and otomycosis
Bustonov M.O., Azizov K.N., Весоv А.А., Dusanova S.B., Kasirova M.Т.
100 patients with chronic sinusitis in combination with chronic otitis media of fungal-bacterial etiology were examined. The control group was formed by 50 chronic otitis media patients.
Clinically, under otomycosis, structural changes appear in three forms: hypertrophic (44%), hydropic (32%) and combined (24%).