EFFECTIVENESS OF BAKTOVEGA THE TREATMENTOF ACUTE AND CHRONIC RHINOSINUSITIS

EFFECTIVENESS OF BAKTOVEGA THE TREATMENTOF ACUTE AND CHRONIC RHINOSINUSITIS

Shamsidinov B.N., Mukhtarova P.R., Tagaimuradova S.F., Olimov T.Kh.

Department of Otorhinolaryngology of State Educational Establishment «Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan»

Aim. Increase the effectiveness of treatment of patients with inflammatory diseases of the paranasal sinuses by applying regional (endonasal) antibiotic therapy.

Materials and methods. The article presents data from a study of 120 patients with acute and chronic rhinosinusitis. Patients were divided into the main and control group of 60 patients. Both groups were matched by sex and age, the nature and duration of the inflammatory process in the paranasal sinuses.

Patients from the main group carried endonasal single intradermal injection of Baktovega (ceftriaxone/sulbactam) in a dosage of 200 mg on the first day of treatment. This method was combined with puncture of the maxillary sinus in the presence of maxillary sinusitis or sinus evacuation — in the presence of sinusitis. Also conducted daily anemisation nasal mucosa, physiotherapy. Also, the patients in this group received oral antihistamines are the second generation.

The control group was treated by the usual method: parenteral antimicrobial in combination with punctures or sine-evacuation, physiotherapy, daily anemizated nasal mucosa and oral intake of antihistamines, second generation. Evaluate the effectiveness of the treatment was carried out at the end of inpatient or outpatient treatment.

Score provided by doctors where 1 — no effect, 2 points — satisfactory effect, 3 points — a positive effect.

Results. 93,3 % of patients, the main group (56 patients), and only 70% of patients in the control group (42 patients) evaluated the effect of treatment as a positive, satisfactory. Effect of treatment indicated 3.3% of the main group (2 patients) and 30% (18 patients) in the control group. Treatment failure was different from the 3,4% in the study group. Consequently, in the study group had more patients (56) with the positive effect of the treatment compared with the control group (42 patients).

Conclusion. Method regional (endonasal) is a highly effective antibiotic therapy, can be used in the treatment of acute exacerbation of chronic rhinosinusitis and also has economic advantages.

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