Tag Archives: efficiency

EFFECTIVENESS OF DIAGNOSTICS AND TREATMENT OF MULTIDRUG RESISTANT FORM OF TUBERCULOSIS

Aim. Examine the effectiveness of diagnostic and effectiveness of treatment of multidrug-resistant tuberculosis in Re¬public of Tajikistan.
Materials and methods. Performed analysis of an officially published statistics on drug-resistant tuberculosis from 2008 to 2012, of the National Center for Tuberculosis Control in the framework of the “Program to protect the population from tuber¬culosis in Republic of Tajikistan for 2010-2015”.
Results. Drug resistance to antituberculosis drugs (anti-TB drugs) started to define with the support of WHO. In 2008 in Dushanbe and Rudaki district (population 324 thousand. man – 13,9% of the countrys population). Cultures studied in supranational laboratory in Gauting (Germany). The first study on drug resistance was conducted in 2008-2009 to the main anti-TB drugs. Multidrug resistance was 16.8% among newly diagnosed patients, including previously treated – 61%. The second study – a test to determine drug susceptibility (DST) – carried out in 2010-2011: cases of MDR-TB were 13% and 53,6%, respectively (a decrease among new cases 3.8% among the patients treated early – on 7,4%).
Conclusion. Obtained results indicate a qualitative improvement of indicators of effectiveness of treatment of patients with MDR-TB in the republic – from 53% to 58,4%, mortality rate decreased from 14,2% to 11,3%.
Key words: efficiency, diagnostics, treatment of drug-resistant forms of tuberculosis

EXPERIENCE OF NOVOSALIK USING IN THE TREATMENT OF ECZEMA

*Kasymov O.I., **Ahmedov F.A., *Kasymov A.O.

EXPERIENCE OF NOVOSALIK USING IN THE TREATMENT OF ECZEMA

*Department of Dermatology and STIs of the State Educational Establishment «Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan»

**Department of Pharmacy of the State Educational Establishment «Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan»

Aim.To study the efficiency of Novosalik in the treatment of eczema.

Materials and methods. The study included 48 patients with eczema aged from 16 to 73 years, with duration of the disease from a few months to 20 years or more. There were 20 men, 28 women, ratio 1:1.4. The age of patients ranged from 16 to 64 years. 8 patients were aged between 16 and 19 years (m – 3, w – 5), from 20 to 29 years – 10 (m – 5, w – 5), from 30 to 39 years old – 12 (m – 5, w – 7), from 40 to 49 years – 8 (m – 4, w – 5), from 50 to 59 years – 5 (m – 3, w – 4), 60 years and older – 5 (m – 2, w – 4). Methods: clinical, statistical, microscopic.

Results. So, itching as the main subjective symptom of eczema in the main group, began to weaken from an average after 3-4 days of treatment, in the control group – after 4-5 days, stopped completely in most patients of the main group to an average of 8-9 day, in all patients – to 12-13 day, in the control group – respectively 11-12 and 14-15 days. Blanching of erythema and edema reduction in the study group began with an average after 3-4 days, their complete disappearance occurred in an average of 15-16 day, in the control group – respectively to 5-6 days and 18-19 days. Infiltration of the skin lesions in patients of the main group began to decrease an average from 6-7 days, fully resolved – to 11-12 day, in the control group – from 8-9 and 14-15 days. Rejection of crusts and scales was from 4-5 days of therapy, culminating in an average to 7-8 day, in the control group – to 6-7 and 10-11 days.

Conclusion. Our studies have shown high efficiency of complex treatment of eczema with Novosalik. Clinical recovery and significant improvement were achieved in 75% of patients, the traditional treatment – only in 60% of patients.