Abstract

Summary

 To study the effectiveness of transscleral diode laser cyclophotocoagulation (TS DL CPC) in patients with various types of refractive glaucoma.
 

Materials and Methods

A dynamic follow-up of patients with secondary glaucoma aged 18 to 67 years was conducted. The procedure was performed on an inpatient basis. Under local anesthesia, patients underwent TS DL CPC. The number of applications varied from 20 to 40 depending on the level of intraocular pressure (IOP) and averaged 33.7. Pulse power ranged from 1.8 to 3.0 J. Exposure time – 3 seconds.

Results

The IOP level in all eyes was high, ranging from 39 to 54 mmHg, with a mean value of 43.2±0.4 mmHg. After TS DL CPC, by the 7th day, IOP reduction to the average statistical norm (19-26 mmHg) was observed in all eyes. The most pronounced IOP reduction was noted in eyes with primary glaucoma, while a less marked effect was observed in eyes with secondary glaucoma.
 

Conclusion

It was established that the use of this method in patients with glaucoma in the terminal painful stage is a good alternative to filtering surgery. Diode laser cyclophotocoagulation effectively reduced IOP, which made it possible to avoid eye removal procedures (evisceration and enucleation).
 

Keywords

glaucoma blindness cyclophotocoagulation intraocular pressure secondary glaucoma.

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References

  1. Ismailova SE, Botabekova TK, Kramorenko YuS. Glaucoma in the structure of ocular morbidity. In: Glaucoma: Problems and Solutions. Moscow; 2024. p. 412-414.
  2. Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2020;90(3):262-267. https://doi.org/10.1136/bjo.2005.081224
  3. Libman ES, Shakhova EV. Blindness, low vision, and visual disability in the Russian Federation. Moscow. 2023: 38-42.
  4. Karim-zade KhJ, Furkatzod F, Makhmadov ShK, Anvarov DzhI. Use of diode laser cyclophotocoagulation in patients with various types of glaucoma. Simurg Natl Med J. 2019;(4):35-39.
  5. Mekhlef MO, El-Haddad NS, El-Ghaffar EA. Outcomes of two patterns of application of subliminal diode laser cyclophotocoagulation in refractory glaucoma: a prospective study. J Egypt Ophthalmol Soc. 2026;119(1):15-23. https://doi.org/10.4103/ejos.ejos_45_25
  6. Abdullahi MI, Musa KO, Olawoye OO, et al. Short-term Efficacy and Safety Outcome of Primary Trans Scleral Diode Laser Cyclophotocoagulation for Primary and Secondary Glaucoma in Nigeria: A Prospective Study. Niger J Ophthalmol. 2025;33(1):22-30. https://doi.org/10.4103/njo.njo_47_24
  7. Chen J, Zhou M, Wang W, et al. Long-term outcomes of transscleral diode laser cyclophotocoagulation in refractory glaucoma. Ophthalmic Surg Lasers Imaging Retina. 2021;52(3):128-135. https://doi.org/10.3928/23258160-20210219-05
  8. Ertan E, Uran M. Transscleral diode cyclophotocoagulation for refractory glaucoma: real-world efficacy and safety. Int Ophthalmol. 2026;46:211. https://doi.org/10.1007/s10792-026-04082-y
  9. Öztürk H, Özen B. Evaluation of diode laser cyclophotocoagulation efficiency in refractory glaucoma and determination of structural changes using ultrasound biomicroscopy. Arq Bras Oftalmol. 2026;89(3). https://doi.org/10.5935/0004-2749.2025-0043
  10. Aquino MC, Barton K. Cyclophotocoagulation: past, present and future. Curr Opin Ophthalmol. 2020;31(2):118-125. https://doi.org/10.1097/ICU.0000000000000638
  11. Salim S. Current variations of cyclophotocoagulation. Dev Ophthalmol. 2022;59:83-95. https://doi.org/10.1159/000522580
  12. Chansangpetch S, Lin SC. Evolving role of laser cyclophotocoagulation. Asia Pac J Ophthalmol. 2023;12(1):23-30. https://doi.org/10.1097/APO.0000000000000553
  13. Lima FE, Sousa DC, Melo GB. Safety and efficacy of transscleral diode laser cyclophotocoagulation. Arq Bras Oftalmol. 2024;87(2):134-140. DOI: needs verification
  14. Kuchar S, Moster MR, Reamer CB. Diode laser cyclophotocoagulation: indications and long-term outcomes. J Glaucoma. 2019;28(7):642-648. https://doi.org/10.1097/IJG.0000000000001268
  15. Shields MB. Textbook of Glaucoma. 7th ed. Philadelphia: Wolters Kluwer; 2023:640-662
  16. World Health Organization. World Report on Vision. Geneva: WHO; 2021: 18-60. https://doi.org/10.2471/BLT.19.249995
  17. Buffault J, Baudouin C, Brignole-Baudouin F, et al. An Overview of Current Glaucomatous Trabecular Meshwork Models. Curr Eye Res. 2023;48(11):1023-1035. https://doi.org/10.1080/02713683.2023.2242916
  18. Wu J, Chen Z, Wang N, et al. Epigenetics of glaucoma in the trabecular meshwork. Clin Epigenetics. 2026;18:16. https://doi.org/10.1186/s13148-025-02039-z