Аннотация

Цель
To determine the prevalence of hyperuricemia (HU) and metabolic syndrome (MS) in patients with type 2 diabetes mellitus (T2DM) and to assess the relationship between serum uric acid levels and the components of MS.
Материал и методы
A total of 191 patients with T2DM hospitalized in the Endocrinology Department of the State Institution “Istiqlol Health Complex” during the period 2023–2025 were examined. HU was diagnosed at serum uric acid levels ≥420 μmol/L in men and ≥360 μmol/L in women. MS was verified according to the NCEP ATP III criteria. Descriptive statistics, the Mann–Whitney U test, χ² test, and Spearman’s correlation analysis were applied
Результаты
The prevalence of MS was 71.2%, and HU – 32.5%. Patients with HU significantly more often presented with obesity (67.7% vs. 48.8%), abdominal obesity (81.6% vs. 55.2%), and arterial hypertension (87.8% vs. 67.8%). Serum uric acid levels positively correlated with waist circumference (WC), triglycerides (TG), and systolic blood pressure (SBP), and negatively with glomerular filtration rate (GFR)
Заключение
Hyperuricemia in patients with T2DM is closely associated with key components of MS and may be considered an additional target for the prevention of cardiometabolic complications.

Ключевые слова

type 2 diabetes mellitus (T2DM) metabolic syndrome (MS) hyperuricemia (HU) uric acid dyslipidemia

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