Аннотация

Цель
To examine the prevalence, clinical and instrumental characteristics, causes, and nature of therapy in patients with Wolff-Parkinson-White (WPW) syndrome
Материал и методы
The study included 42 patients (26 men and 16 women) who were hospitalized for various cardiovascular pathologies with WPW syndrome and treated in the cardiology departments of the State Institution «Istiklol Health Complex» during the period 2018-2022. The analysis included demographic data, WPW etiology, electrocardiography (ECG) and Holter ECG characteristics, echocardiography (EchoCG) to assess structural heart abnormalities, clinical manifestations, methods of relieving atrioventricular reciprocating tachycardia (AVRT), and the nature of the therapy administered.
Результаты
The average age of patients was 31±13.5 years. The majority (38.1%) belonged to the 21-30 year age group. In 69% of cases, WPW syndrome was associated with congenital anomalies, with additional links to chronic rheumatic heart disease (9.5%) and hypertrophic cardiomyopathy (14.3%). AVRT was recorded in 35.7% of patients based on ECG data, with manifest WPW detected in 80.9% of cases. The most common symptoms of the disease were palpitations (64.3%) and weakness (61.9%), while syncope or episodes of loss of consciousness were noted in 11.9% of patients. AVRT treatment included the use of amiodarone, which showed high effectiveness, along with beta-blockers and calcium channel antagonists
Заключение
WPW syndrome is a common form of ventricular preexcitation, frequently associated with congenital heart anomalies. The manifest WPW form prevails. The high frequency of extrasystoles and AVRT highlights the risk of life-threatening arrhythmias in WPW patients. The significant duration of symptoms prior to diagnosis necessitates increased physician awareness and screening ECG examinations.

Ключевые слова

Wolff-Parkinson-White (WPW) syndrome electrocardiography (ECG) causes therapy.

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Список литературы

  1. Aringazina R.A., Musina A.Z., Zholdasova N.Zh., et al. Pathogenesis, diagnosis, and catheter ablation peculiarities of Wolff-Parkinson-White syndrome. Kardiologicheskiy vestnik-Cardiology Bulletin. 2023, Vol. 18, No. 3, pp. 29–34.
  2. Zaglieva S.S., Mammaev S.N., Zagliev S.G., et al. Paroksizmial’nye narusheniya ritma serdtsa pri sindrome Vol’fa-Parkinsona-Uayta [Paroxysmal heart rhythm disorders in Wolff-Parkinson-White syndrome]. Vestnik Dagestanskoy gosudarstvennoy meditsinskoy akademii-Bulletin of the Dagestan State Medical Academy. 2021, No. 1(38), pp. 55–62.
  3. Tolstokorova Y.A., Nikulina S.Y., Chernova A.A., et al. Clinical, electrophysiological, and molecular genetic characteristics of patients with Wolff-Parkinson-White syndrome (literature review). CardioSomatika. 2023, Vol. 14, No. 1, pp. 59–66.
  4. Tolstokorova Y.A., Nikulina S.Y., Chernova A.A., et al. Investigation of PRKAG2 and PRKAG3 genes in patients with Wolff-Parkinson-White syndrome. Rossiyskiy kardiologicheskiy zhurnal-Russian Journal of Cardiology. 2023, Vol. 28, No. 10, pp. 53–56.
  5. Huizar J.F., Kaszala K., Tan A., Koneru J., Mankad P., Kron J., Ellenbogen K.A. Abnormal Conduction-Induced Cardiomyopathy. J. Am. Coll. Cardiol. 2023, Vol. 81, pp. 1192–1200.
  6. Książczyk T.M., Jaroń A., Pietrzak R., Werner B. Assessment of the physical performance in children with asymptomatic pre-excitation. Europace. 2021, Vol. 24, pp. 855–859.
  7. Skov M.W., Rasmussen P.V., Ghouse J., et al. Electrocardiographic preexcitation and risk of cardiovascular morbidity and mortality: Results from the Copenhagen ECG study. Circ Arrhythm Electrophysiol. 2017, Vol. 10, pp. e004778.
  8. Vătășescu R.G., Paja C.S., Șuș I., et al. Wolf-Parkinson-White syndrome: Diagnosis, risk assessment, and therapy—an update. Diagnostics (Basel). 2024, Vol. 14, No. 3, pp. 296.