Category Archives: 2013

TREATMENT AND PREVENTION OF VIRAL INFECTIONS WITH THE USE OF INTERFERON INDUCTORS

MIRZOYEVA Z.A., KHISOMOVA KH.K.
THE DEPARTMENT OF FAMILY MEDICINE TIPGPMP
Today viral infections are the leading cause of morbidity worldwide, the role of which in the overall morbidity will only increase. Recently in the treatment of viral infections extensive use of immunomodulators, the range is constantly expanding. The most promising drugs in the given as¬pect are interferon inducers. The article presents the results of studies of prophylactic effectiveness and treatment of acute respiratory viral infections interferon inducers of 150 patients aged from 1 month to 17 years. The results obtained showed that anaferon having a pronounced curative and prophylactic efficiency of the flu, when before vaccine period increases the functional activity of specific antibodies that reduce the intensity of morbidity. The ability of the drug to reduce the number of bacterial complications allowed authors to effectively apply anaferon in the treatment of viral infections in children with secondary immunodeficiency condition. The inclusion of anaferon in the standard therapy of acute intestinal virus infection in children significantly reduced the duration of the main symptoms of the disease.

ULTRASOUND DIAGNOSTICS THYROID PATHOLOGY IN CHILDREN AND ADOLESCENTS

KASYMOVA S.D., AYUBOVA G.SH., RAHMONOV V.D., BOYMATOVA M.B.
THE COURSE OF ENDOCRINOLOGY AT DEPARTMENT OF THERAPY TIPGPMP REPUBLICAN CLINICAL CENTRE OF ENDOCRINOLOGY
In connection with the exceptional importance of the thyroid gland problem of pathology of the organ of children is the focus of endocrinologists. Pathology of the thyroid gland in the regions of iodine deficiency, which includes the Republic of Tajikistan, occupies the leading position in the endocrine pathology in children and adolescents. Diagnostics of thyroid pathology in this category includes a phased investigation with the decision of the question concerning the goitrous increase the authority and assessment of the functional state of the thyroid gland. Many tasks successfully done with the use of ultrasonic technologies. The article suggests the use of ultrasound diagnostics for estimation of structural and functional changes of the thyroid gland, 93 children and adolescents with a duration of pathology from 6 months to 2 years. Depending on the functional state of the examined organ children and adolescents were divided into the following groups: I group amount¬ed to 61,3% of patients with diffuse nontoxic goiter, II – 20,4% of individuals autoimmune, with tireoidita III group – 18,2% of surveyed with hypopituitarism thyroid gland. Results of ultrasonic research show the greatest increase in volume of the thyroid gland in the group 2 patients with au¬toimmune thyroiditis. Analysis of results of ultrasonic research showed that in the 1 group of the examined enlargement of the thyroid gland was moderately expressed. The largest increase of the volume of the thyroid was noted in group 2 patients with autoimmune thyroiditis. Of the 17 patients with subclinical hypothyroidism last group in 58% of cases of thyroid volume slightly increased in 42% of cases, the value remains in the normal range. The results obtained allow to note that for the estimation of structural and functional changes of the thyroid gland are essential ultrasound diagnostics.

THE EFFECTIVENESS OF THERAPY IMMUNOSTIMULATING ONYCHOMYCOSIS IN ELDERLY AND SENILE AGES

KASYMOV O.I., KASYMOV A.O.
THE DEPARTMENT OF DERMATOVENEROLOGY OF TIPGPMP
The article shows the efficiency of complex method of treatment of mycosis stop with onychomycosis in elderly and senile ages using immunostimulant thymocine 45 patients aged 60 to 85 years. Using methods of bacteriological research, 64.4% of the patients were grown culture of Trichophyton rubrum, in 11.1% of Trichophyton mentagrophytis var.interdigitale, in 24.4% – fungi not sown. Intertriginous form of mycosis stop diagnosed in 12 patients, dishydrotic – 6, mixed – 18. Combination squamous and intertriginous forms was observed in 11 patients, squamous, dishydrotic and intertriginous – for 7. The erased form of mycosis stop was noted in 9 patients. Immediate and remote results of treatment showed a significant advantage of an integrated method of treatment with the application of immune system stimulant. By the end of 6 months of follow-up highly effective results when immunostimulating therapy were achieved in 83,3% of patients in the group of patients treated without immunomodulator, efficiency indicator accounted for 61.9%. Among patients with total-dystrophic and proximal forms of combined treatment of onychomycosis gave clinical and mycological recovery in 66.7%, without immunostimulant – only 50%. The average speed of growth of nail plates stop in complex treatment using thymocine amounted to 1.37±0.06 mm per month, which is much faster than in the treatment only systemic antimycotics. The obtained results have shown the effectiveness of immunostimulating method of treatment of athlete’s foot with onychomycosis, compared with the traditional.

SITUATIONAL ASSESSMENT OF THE RESULTS OF TREATMENT ABSENCE OF TEETH REMOVABLE DENTURES

KARIMOV S.M., GUREZOV M.R., YERAKOV F.M.
THE DEPARTMENT OF THERAPEUTIC STOMATOLOGY TIPGPMP
To study the results of orthopedic treatment of occlusive defects removable dentures assessed the state of orthopedic status of the oral cavity in 198 patients aged 20 to 60 years and older. In patients examined dentures are the most used in combined defects of dentitions, singly standing tooth in the jaw, and at the end defects. The least dentures are used when included occlusive defects. The number of removable dentures made on the upper and lower jaw, respectively 49,3% and 50,7%. The share of clasp prostheses made of the lower jaw with partial absence of teeth, amounted to 54,6 per cent. In the absence of teeth laminar dentures in 61,4% of the cases were made in the upper jaw. The largest number of laminar dentures (37,4%) had a life span 3 to 5 years. There was a significant predominance of the laminar dentures in need of re-manufacturing, over clasp, the service life of up to 5 years. If a period of more than 5 years, the number of clasp dentures exceeds the number of laminar. Comparing the reasons for replacement of removable dentures with partial absence of teeth, it can be noted that the leading position clasp prostheses occupy complications associated with fractures of the abutment teeth, laminar – breakdown of prosthesis (38,7%) and aesthetic dis¬orders (13,6%). The main causes of alteration of a laminar dentures were bad fixation (45,4%) and breakage of prosthesis (29,4%). Aesthetic disorders amounted to 13,4%, 8,8% of cases the cause of re-prosthetics was a subjective desire of the patient, 2,9% of cases – other reasons.

THE IMPACT OF INDIRECT ELECTROCHEMICAL OXIDATION THE TOXICITY OF BLOOD IN PATIENTS IN THE TERMINAL PHASE OF PERITONITIS, DUE TO PANCREONECROSIS

DOSTIEVA Z.A., SHUMILINA O.V., MURADOV A.M., HAMROKULOV A.A.
THE DEPARTMENT OF EFFERENT MEDICINE AND INTENSIVE THERAPY TIPGPMP
In 15 patients with pancreonecrosis complicated by the terminal phase of peritonitis, we estimated the effect of indirect electrochemical blood oxidation on the state of the detoxification function of the lungs by intravenous 0,06% solution of sodium hypochlorite. To study the detoxification function of the lungs compared the blood of the right ventricle of the heart and arterial blood from radiotherapy or femoral artery, taken simultaneously. Study was carried out after 1 and 4-6 h after infusions of the mentioned solution. If, prior to the infusion of sodium hypochlorite concentration of urea and creatinine in the blood drains were reliably higher than in streams to the light respectively by 20,9% and 12,9%, for 1 hour, these figures are reduced to the respective indicators of 18,2% and 7,6%, and after 6 hours of light to see themselves their detoxifying that points to the restoration of detoxification functions of the body. The results obtained showed that sodium hypochlorite solution is a powerful oxidant toxic blood components, primarily amphiphilic, hydrophilic and hydrophobic metabolites, are in low – small and medium molecular fractions, as well as lipid structures of cell membranes due to changes in their perme¬ability and mode of operation. The use of a solution in the first 4-6 hours causes significant improvement detoxification function of the lungs and its recovery depending on the stage of the infringement.

ENDOVIDEOSURGICAL TREATMENT OF ECHINOCOCCOSIS OF THE LIVER

GUL’MURADOV T.G., SANGOV D.S., NAZAROV F.N.
THE DEPARTMENT OF CARDIOVASCULAR AND RECONSTRUCTION SURGERY TIPGPM RSCSSH MPH RT
To conduct comparative assessment of the results videolaparoscopycal and traditional echi-nococcectomya of liver and improve the results of surgical treatment of echinococcosis of the liver using videolaparoscopycal technology analyzes the results of surgical treatment of 206 patients with echinococcosis of liver aged 15 to 64 years. 96 patients operated with the use of videolaparoscopycal technology (main group) and 110 – traditional way (control group). Indi¬cation for use videoendosurgical technology was the presence of uncomplicated echinococcosis cysts of the liver in zones good view, not lying deep into the parenchyma, with a diameter of 10 cm in the absence of signs of sepsis, and a breakthrough in the bile ducts. When diagnostic laparoscopy in 6 cases was detected intrahepatic localization cysts, Two patients detected adhe¬sions in subdiaphragmatic space, in 2 cases visualize echinococcosis cysts failed. To substantiate the high efficiency and minimal invasiveness of laparoscopic technology in comparison with traditional echinococcectomya of the liver. Thanks to the use of videolaparoscopycal technol¬ogies, elimination of the biliary fistula, ultrasonic cavitation and omentoplastic residual cavity cysts, significantly decreased the frequency of postoperative complications, reduced the period of inpatient treatment, decreased cost of surgical treatment.

THE NATURE OF THE PAIN SYNDROME IN PATIENTS WITH ADVANCED STAGES OF MALIGNANT NEOPLASMS MAXILLOFACIAL AND EFFICIENCY TRADITIONAL PAIN THERAPY

GAFAROV H.O., SHAKIROV M.N., MIRZOEV M.SH.
THE DEPARTMENT OF MAXILLOFACIAL SURGERY WITH CHILDREN STOMATOLOGY OF TIPGPMP
Questionnaire of 108 patients with advanced stages of malignant tumors of maxillo-facial region studied the nature of the chronic pain syndrome and assessing the effectiveness of traditional pain therapy. The 58,3% of the observed diagnosed with advanced stage cancer of mucous membranes of the oral cavity, 23.1% of installed cancer of mucous membrane of the maxillary sinus, a 3.7% identified advanced stage of osteosarcoma jaws. The 3rd and the 4th stage of malignant process revealed respectively of 17.6% and 82.5% of the observed. Among patients with the character of the pain syndrome and effectiveness of the analgetic therapy were studied by the method of questioning on the specially prepared questionnaire. Study of the dynamics of pain syndrome showed that the pain intensified after their first appearance during the first 3 months of 20,3% of patients during 3-6 months – 37,0%in 6-12 months in 25,9%, later than 1 year – 16,6% of patients. Analysis of the nature of pain showed that 37.9% of persons they are «Ripper» character, 27.7% of «capturing», 23.1% of the «hot», 6,5% – «breaking», 4.6% – «whining». It is established that the pain syndrome in this category of patients is often neuropathic development mechanism, which explains the lack of effectiveness of pain therapy using drugs. The findings suggest the need for further improvement of the well-known methods and search for new, more effective methods of reduction of chronic pain syndrome in this category of patients.

ESTIMATION QUALITY OF CONSTRUCTIVE FEATURES NON-REMOVABLE PROTHESIS IN ORAL CAVITY

ASHUROV G.G., KARIMOV S.M.
THE DEPARTMENT OF THERAPEUTIC STOMATOLOGY TIPGPMP
To determine the frequency of various types of fixed prosthesis in need of re-manufacture, conducted clinical and epidemiological study of orthopedic status in 264 patients, including men and women, respectively, 62,10% and 37,9%. All examined patients previously received orthopedic treatment and had dentures in the oral cavity. Age range, the largest group comprised patients older than 60 and 50-59 years (according to 34,5% and 27,2%). IN patients with partial absence of teeth investigated 1167 fixed prosthesis in need of re-manufacture, among which 66.1% was forged-soldered lined or without it, 29,8% – solid lined or without it, 3,2% – plastic and 0,9% -ceramic. Among fixed prosthesis oral prevail forged-pressure welded prostheses, the number of which was two times more than one, and twenty times more, than plastic and ceramic. Service life of 5 to 7 years have 37,6% of one-piece prostheses, life for over 7 years – 36,25% one-constructions without facing. Dominated by the share of remade one-piece designs over forged-soldered in a pe¬riod of use up to 7 years. After a seven-year term of use of an increase in the share forged-soldered prostheses, compared with the solid. The most common causes of withdrawal of fixed prosthesis were aesthetic disorders and the need to manufacture additional dentures.

ON THE ROLE OF SPECIALIZED MEDICAL ASSISTANCE IN MODERN CONDITIONS IN THE REGIONAL HOSPITAL NAME A. HAGHNAZAROV THE CITY OF KULYAB

AKHMEDOV A., KABIROV A., TAVACALOVA M.
THE DEPARTMENT OF PUBLIC HEALTH, ECONOMY, MANAGEMENT BY PUBLIC HEALTH WITH COURSE OF THE MEDICAL STATISTICS OF TIPGPMP
KHATLON REGIONAL HOSPITAL №2 NAME A.HAGHNAZAROV THE CITY OF KULYAB
One of the main directions of improving the quality of medical care is its specialization, which gives a broad and qualitative information on the human health and the factors that disturb it. High-quality medical assistance, as an objective process of development of a science and prac¬tice, cannot develop in isolation from the improvement of the overall health system. With the purpose of studying of quality of rendering of specialized medical aid to the analysis of 16034 static cards of the patients for the period from 2009 to 2012, During the monitoring period, of the total number of hospitalized residents of the city amounted to 32,3%, 67,7% came from rural areas. For three years in the gastroenterology Department received 1387 patients, among which the urban and rural residents amounted to 30,3% and 69,7 percent respectively. Out of the total number of hospitalized patients 99,9% of rural residents were delivered later than 24 hours of onset due to the fact that the rugged mountain terrain, climate conditions and problems of road infrastructure are the difficulty in timely delivery. In the statistical analysis revealed that women get sick more often, however, the mortality rate of men exceeds that of women is almost twice; the mortality rate among rural inhabitants exceeds the mortality rate of urban 3.5 times. Obtained in the course of the study, data demonstrate the necessity of conducting sociological survey to identify the factors affecting the availability, timeliness and quality specialized medical assistance to the population of rural areas.

TO QUESTION ABOUT PREVALENCE AND INTENSITIES OF ENDOPERIAPICAL’S COMPLICATIONS IN DENTISTRY PRACTICE (REVIEW OF THE LITERATURE)

TURAEV N.G., ISMOILOV A.A.
Endoperiapical’s syndrome often is a reason of odontogenic inflammatory processes of the max¬illa-face area, including sharp odontogenic sepsis, odontogenic mediastinitis and inwardlyskull’s of inflammatory processes.