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СЛОВО ГЛАВНОГО РЕДАКТОРА
Наше издание является научно-практическим журналом, в котором публикуются основные научные результаты диссертаций на соискание ученой степени кандидата и/или доктора медицинских наук как нашего института, так и других лечебно-учебных медицинских учреждений, интересные случаи из практики, обзоры литературы, лекции и юбилейные статьи. Журнал выходит 4 раза в год, и каждый номер имеет не менее 80 страниц. Каждая поступающая статья принимается по требованиям, проходит строгий отбор и отдается для выпуска в номер только после рецензирования и обязательного редактирования.
У нас принято одностороннее слепое рецензирование. Рецензенты уделяют особое внимание содержанию статьи и проверке данных статистической обработки, их соответствие современным требованиям.
Главный редактор журнала доктор медицинских наук Мухиддинов Н. Д.-
THE ORGANIZATION AND ACTIVITY OF DIAGNOSTIC SERVICE OF THE VARIOUS COUNTRIES (THE LITERATURE REVIEW)
SAFAROVZ.SH.,AHMEDOVA.A., MAHKAMOVK.K.
Thus, the literature review has shown that diagnostics as scientific discipline, devel-oped in indissoluble communication with other scientific disciplines. The key moment of its development was the wide experience of great scientific Gippokrata, Galena, Avitsenny, and also the organization of school of medicine in the countries of the East, Asia, Europe. Formation of the diagnostic centers, as in Europe, America, and in the countries of the former USSR became an important stage of development of diagnostic service. Activity of the kliniko-diagnostic centers shows their conclusive advantage and rather considerable role in public health services system. Thus efficiency of activity providing at the expense of introduction of the expensive equipment, modern methods of research and presence of highly-skilled personnel. -
COGNITIVE IMPAIRMENT IN CEREBROVASCULAR DISEASE (PART I)
ABDURAKHMANOVA R.F., IZZATOV H.N., HADIBAEVA G.R., SHARIPOVA B.A.
DEPARTMENT OF NEUROLOGY AND MEDICAL GENETICS OF STATE EDUCATIONAL ESTABLISHMENT «INSTITUTE OF POSTGRADUATE EDUCATION IN HEALTH SPHERE OF REPUBLIC OF TAJIKISTAN»
Cerebrovascular disease is one of the most important medical and social problems. One of the serious consequences of cerebrovascular disease, is a disorder of cognitive functions. Cognitive disorders (CD), along with other neuro¬logical disorders are important manifestations of organic brain pathology. Vascular CD in its development through several stages, and the most severe form of cognitive disorders, vascular dementia is (VD). At the CD is dominated neuropsychological symptoms of frontal dysfunction than memory impairment, as well as the presence of neurological symptoms in the early stages of the disease. The main factors of the development of the CD are: arterial hypertension, atherosclerosis, heart disease, diabetes, etc. These factors contribute to the development of lacunar infarcts and leukoaraiosis that precede as moderate CD, well as dementia.
In patients with diabetes are found in 87% of cases of depressive disorders. Joining depression to vascular lesions of the brain, leading to a deepening of the CD. The link between depression and vascular disease is determined by hemo¬ dynamic factors, which manifests itself in an increase in blood pressure and a decrease in cardiac output in response to the different emotions of the subjects. Also in depressive disorders marked hypercoagulable syndrome. Neuroimaging techniques reveal functional changes in the brain, depression as a reduction in blood flow and glucose metabolism, mainly in the areas responsible for cognitive functions. -
THE MAIN REASONS, TERMS OF ENTRANCE AND ACCOMPANY PATHOLOGY OF PATIENTS WITH STROKE ON THE EXAMPLE OF DEPARTMENT OF REANIMATION OF A CITY SCIENTIFIC CENTER OF REANIMATION AND DETOXIFICATION AND SUGHD REGIONAL HOSPITAL
Aim. Analysis of results of the main causes, risk factors, period of receipt and accompanying pathology in patients with acute infringement of cerebrovascular circulation of the blood admitted to the reanimation department of a city scientific center of reanimation and detoxification in Dushanbe and Sughd Regional Hospital in 2012-2014.
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COMPARATIVE CHARACTERISTICS OF MALARIA INHABITANTS OF THE BORDER AREAS OF THE KHATLON REGION OF THE REPUBLIC OF TAJIKISTAN.
AKHMEDOV A., SHARIPOV A. A., NARZULOEVA M. F., SHARIPOVA SH. T., TOLIBOV A. H.
Thus we can assume that of the anti-malaria activities only intensified in the border areas of Tajikistan with the Islamic State of Afghanistan persistent results to restrict importation of malaria mosquitoes can not give. In this connection it is necessary to undertake joint efforts for anti-malaria activities in the northern areas bordering Tajikistan the Islamic State of Afghanistan in order to create a barrier of the border zone, a depth of at least 10 – 15 km, in which mosquito measures should be implemented after termination of the rest of the country. -
The allergy and immunological reactivity in highland places the patients who have eczema
Khaydaralieva Sh., Kasymov O.
Quantivalent crossed sensitization in the majority of 31 examined highland eczema patients (men – 17, women – 14) at the age of 18-55 was revealed in the order of decrease to domestic, alimentary, epidermal, drug and pollen allergens. Immunological disorders were characterized by diminution of CD3-lymphocytes, increase of IgE by 1.9, IgG by 1.3 and of circulating immune complexes by 1.4, as well as by lessening of white cell’s phagocytic activity and of the phagocytic number. Immunological disturbances depend on the duration and severity of the disease.
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COMPARATIVE EVALUATION OF EFFICIENCY APPLICATION OF MODERN METHODS OF DIAGNOSTICS TOXIC BLOOD COMPONENTS DURING ENDOTOXEMIA
TUYCHIBOEVA M.N., MURADOV A.M. SHUKUROV T., SHUMILINA O.V.
COURSE “LABORATORY WORK” TIPGPMP
One of the most urgent problems in the structure of modern somatic pathology remains endo¬toxicosis, which is a basic component of the formation of the severity of the General condition. The article presents the results of analysis of toxic blood components 206 patients endotoxemia developed in the result of acute renal failure, peritonitis and septicemia in comparison with the figures of 20 healthy donors. Material for the study served as the blood of patients aged from 17 to 62 years, of which men made up 59,3% of women – 40,3%. The study used biochemical, gel-chromatography and infrared spectroscopic methods of diagnostics indicators token to reflect the level of intoxication. Found that the toxicity index in patients endotoxemia increases by more than 700%, compared with the control. On the basis of carried out research we can conclude that the patients endotoxemia occur intensification of lipid peroxidation, depression of immunity, reduction in antioxidant protection and detoxification abilities of organism. The comparison of the curves fractionation of blood plasma during endotoxemia and in healthy people showed that the patients of the main group there was a significant increase in fractions of A and D, to a lesser extent faction Century There was a tendency to a decrease in blood levels of medium-weight molecules due to their concentration redistribution that may be characteristic only for endotoxicosis -
The medical of terminology’s tajik language in modern conditions
Fathulloev T. F., Usupov A. N., Shekhov A.M.
This article indicates that one of necessary conditions for use of medical terminology is the brevity and the pithiness which in many medical institutions isn’t observed. Besides in documentation analysis medical establishments the logic and unscientific content of many expressions and the offer, the wrong transfer and inexact terminology in the medical dictionary, and such mistakes in word-formation by means of suffixes is revealed.
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Intrarenal hemodynamics at the typhoid fever, complicated by acute renal failure
Sangov M. S., Muradov A. M., Rahmonov E. R.
Results of research of patients are given in work by a typhoid, complicated sharp nephritic insufficiency at which indicators in nephritic haemo dynamics were studied. By researches at different levels of nephritic haemo dynamics it is proved that it directly depends on system or central haemo dynamics, decrease in indicators of UO, UI, SI and in-crease in OPSS, and also pulmonary pressure that leads to authentic decrease in a blood-groove in a nephritic artery which depends on weight of OPN, degree of a gipovolemiya and endogenny intoxication at a typhoid. -
THE INTERACTION OF THE MYOCARDIUM IN PATIENTS WITH CORONARY HEART DISEASE AGAINST THE BACK¬GROUND OF DILATATION OF BOTH VENTRICLES
SAMADOV SH.KH., KOKSHENEVA I. V., BUZIASHVILI Y.I., ELTANAZAROV M.D.
The results obtained demonstrate the close interconnection of the two ventricles, which increases with the progression of their dilatation. The main mechanism of implementation of the interventricularinteractions is the limitation of the pericardium. Pericardium by creating a rigid limited amount for the four chambers of the heart and increases the influence of diastolic volume of one chamber to another, calling it the configuration changes and influencing the characteristics of its content. Another possible mechanism of implementation of the diastolic interventricularinteraction – deformation of the ventricles, which takes place in the ratio of forces in the ventricular septum (transseptalpressure gradient) and the severity of structural changes of the ventricles. -
Diagnostics of osteoporosis under psoriatic arthropathy
Kholova Z.U.
Osteopenic syndrome is the pure complicated PA. The development of osteoporosis under PA associate with high activity, gravity pathologic process, intake of glucocorticosteroids. In patients of PA with complicated osteoporosis have pains evident pain syndrome in bones in comparison with patients, that haven’t osteoporosis.